Review





Similar Products

cox iv 11242 1 ap rabbit  (Proteintech)
96
Proteintech cox iv 11242 1 ap rabbit
Cox Iv 11242 1 Ap Rabbit, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cox iv 11242 1 ap rabbit/product/Proteintech
Average 96 stars, based on 1 article reviews
cox iv 11242 1 ap rabbit - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier
rabbit anti cox 2  (Proteintech)
96
Proteintech rabbit anti cox 2
Rabbit Anti Cox 2, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti cox 2/product/Proteintech
Average 96 stars, based on 1 article reviews
rabbit anti cox 2 - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier
anti cox4i1 antibody  (Boster Bio)
90
Boster Bio anti cox4i1 antibody
Anti Cox4i1 Antibody, supplied by Boster Bio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti cox4i1 antibody/product/Boster Bio
Average 90 stars, based on 1 article reviews
anti cox4i1 antibody - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
rabbit polyclonal anticox 1  (Proteintech)
93
Proteintech rabbit polyclonal anticox 1
Rabbit Polyclonal Anticox 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal anticox 1/product/Proteintech
Average 93 stars, based on 1 article reviews
rabbit polyclonal anticox 1 - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
anti cox iv  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc anti cox iv
Anti Cox Iv, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti cox iv/product/Cell Signaling Technology Inc
Average 94 stars, based on 1 article reviews
anti cox iv - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
anti cox 2  (Cell Signaling Technology Inc)
98
Cell Signaling Technology Inc anti cox 2
Anti Cox 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti cox 2/product/Cell Signaling Technology Inc
Average 98 stars, based on 1 article reviews
anti cox 2 - by Bioz Stars, 2026-03
98/100 stars
  Buy from Supplier
cox4  (Cell Signaling Technology Inc)
97
Cell Signaling Technology Inc cox4
Single cell analysis of TAX1BP1 translocation to mitochondria after CCCP- mediated depolarization. ( A ) Representative immunofluorescence images showing TAX1BP1 (yellow), parkin (magenta) and SSBP1 (cyan) after mitochondria depolarization in 5KO HeLa cells. Solid arrowheads indicate TAX1BP1 structures co-localizing with mitochondrial material. Arrows indicate TAX1BP1 structures not engaged with mitochondrial material. ROI 1 represents > 50 % of cell population while ROI 2 represents < 50% of cases. Scale bars: 10 µm. Zoom insets for WT (i), TAX1BP1 K549R (ii), TAX1BPΔCC3 (iii and iv) are shown. ( B ) Mean mitochondrial size of SSBP1 foci after 4h CCCP. ( C-D ) Normalized SSBP1 (C) area or (D) perimeter per cell. ( E ) Correlation analysis of the percentage of mitochondrial area recognized by TAX1BP1 (X axis) in relation to the percentage of total TAX1BP1 found on mitochondria (Y axis). Significance p-values are indicated in the graph for the indicated TAX1BP1 constructs. ( F ) Left panel: quantitative analysis of WT, TAX1BP1 K549R or TAX1BP1ΔCC3 localization after mitochondria depolarization in 5KO-PRKN cells after mitophagy induction (4h CCCP). TAX1BP1 localization is classified between cells where <t>COX4</t> clumps are fully recognized by TAX1BP1 (complete apposition) and cells where COX4 clumps recognition is limited (localized apposition). Bars: mean ± SEM. Right panel: representative immunofluorescence images stained for TAX1BP1 (yellow) and COX4 (magenta) are shown for each category.
Cox4, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cox4/product/Cell Signaling Technology Inc
Average 97 stars, based on 1 article reviews
cox4 - by Bioz Stars, 2026-03
97/100 stars
  Buy from Supplier

Image Search Results


Single cell analysis of TAX1BP1 translocation to mitochondria after CCCP- mediated depolarization. ( A ) Representative immunofluorescence images showing TAX1BP1 (yellow), parkin (magenta) and SSBP1 (cyan) after mitochondria depolarization in 5KO HeLa cells. Solid arrowheads indicate TAX1BP1 structures co-localizing with mitochondrial material. Arrows indicate TAX1BP1 structures not engaged with mitochondrial material. ROI 1 represents > 50 % of cell population while ROI 2 represents < 50% of cases. Scale bars: 10 µm. Zoom insets for WT (i), TAX1BP1 K549R (ii), TAX1BPΔCC3 (iii and iv) are shown. ( B ) Mean mitochondrial size of SSBP1 foci after 4h CCCP. ( C-D ) Normalized SSBP1 (C) area or (D) perimeter per cell. ( E ) Correlation analysis of the percentage of mitochondrial area recognized by TAX1BP1 (X axis) in relation to the percentage of total TAX1BP1 found on mitochondria (Y axis). Significance p-values are indicated in the graph for the indicated TAX1BP1 constructs. ( F ) Left panel: quantitative analysis of WT, TAX1BP1 K549R or TAX1BP1ΔCC3 localization after mitochondria depolarization in 5KO-PRKN cells after mitophagy induction (4h CCCP). TAX1BP1 localization is classified between cells where COX4 clumps are fully recognized by TAX1BP1 (complete apposition) and cells where COX4 clumps recognition is limited (localized apposition). Bars: mean ± SEM. Right panel: representative immunofluorescence images stained for TAX1BP1 (yellow) and COX4 (magenta) are shown for each category.

Journal: bioRxiv

Article Title: Parkin-dependent ubiquitination of TAX1BP1 directs efficient autophagic removal of defective mitochondria

doi: 10.1101/2025.05.16.654474

Figure Lengend Snippet: Single cell analysis of TAX1BP1 translocation to mitochondria after CCCP- mediated depolarization. ( A ) Representative immunofluorescence images showing TAX1BP1 (yellow), parkin (magenta) and SSBP1 (cyan) after mitochondria depolarization in 5KO HeLa cells. Solid arrowheads indicate TAX1BP1 structures co-localizing with mitochondrial material. Arrows indicate TAX1BP1 structures not engaged with mitochondrial material. ROI 1 represents > 50 % of cell population while ROI 2 represents < 50% of cases. Scale bars: 10 µm. Zoom insets for WT (i), TAX1BP1 K549R (ii), TAX1BPΔCC3 (iii and iv) are shown. ( B ) Mean mitochondrial size of SSBP1 foci after 4h CCCP. ( C-D ) Normalized SSBP1 (C) area or (D) perimeter per cell. ( E ) Correlation analysis of the percentage of mitochondrial area recognized by TAX1BP1 (X axis) in relation to the percentage of total TAX1BP1 found on mitochondria (Y axis). Significance p-values are indicated in the graph for the indicated TAX1BP1 constructs. ( F ) Left panel: quantitative analysis of WT, TAX1BP1 K549R or TAX1BP1ΔCC3 localization after mitochondria depolarization in 5KO-PRKN cells after mitophagy induction (4h CCCP). TAX1BP1 localization is classified between cells where COX4 clumps are fully recognized by TAX1BP1 (complete apposition) and cells where COX4 clumps recognition is limited (localized apposition). Bars: mean ± SEM. Right panel: representative immunofluorescence images stained for TAX1BP1 (yellow) and COX4 (magenta) are shown for each category.

Article Snippet: The following primary antibodies were used: CD63(1:250, Antibodies online, ABIN94214), COX4 (1:10000, Cell signaling, 4850), HIS-tag (1:500, Addgene, 184180), HSP60 (1:1000, Novus Biologicals, NBP3-05536), LC3B (1:500, Cell signaling, 835065), Parkin(1:10000, Cell signaling, 4211S), RAB7 (1:200, Cell signaling, 95746), TAX1BP1 (1:500, Novus Biologicals, NBP1-86662), VPS35 (1:250, Novus Biologicals, NB100-1397).

Techniques: Single-cell Analysis, Translocation Assay, Immunofluorescence, Construct, Staining